The Vice President, Head of Translational Medicine, Oncology is a key scientific leader and integral member of the Translational Medicine leadership team accountable forall translational research for gRED (Genentech Early Research & Development) early stage oncology portfolio and Roche's late stage oncology portfolio spanning multiple therapeutic modalities. This person will lead a global team (110+ individuals) of translational scientists responsible to advance research discoveries into novel cancer therapies, discover and develop novel biomarkers and strategies to support clinical trials, and derive new research directions and drug discovery insights from patient samples and data.

This leader will oversee the development and execution of innovative biomarker strategies to drive preclinical and clinical development across a rich pipeline of investigational cancer therapeutics through all phases of the portfolio. In addition, the leader will oversee foundational and disease-oriented translational research to maximize scientific and clinical impact and drive drug discovery.

Reporting directly to the Head of Translational Medicine, the VP, Global Head of Translational Medicine Oncology requires an individual to possess a cross enterprise (borderless) mindset with outstanding communication and leadership skills that enable collaboration across the Roche organization and the ability to build and facilitate strong relationships externally. This individual will work closely with leaders across Research, Early Clinical Development, Computational Sciences, and Development Sciences in gRED, and Product Development, Medical Affairs and Global Product Strategy (GPS), Spark, FMI as well as global functions across the Roche organization to contribute to strategies to discover and develop impactful therapies that provide transformative benefit for patients.

This individual must be viewed as a scientific expert and strategic thought leader, who can readily bridge cutting edge translational medicine environments with a fast-paced clinical organization. They will be a scientific expert and key influencer at many governance committees including, but not limited to the Research Review Committee (RRC), Development Review Committee (DRC), and late stage therapeutic area committees and will as a member of the Translational Medicine Leadership team will help shape and guide the Translational Medicine organization.

Key Duties and Responsibilities:

* Accountable for the scientific impact and accomplishments for all Translational Medicine Oncology portfolio from Early Development through approval / Life Cycle planning of a global organization through influential, innovative, inspirational and strategic excellence

* Expand the translational research strategy using novel and innovative approaches to identify new mechanisms of response and resistance, combination therapies, biomarkers, patient segments, and/or new targets.

* Build and strengthen the scientific impact of Translational Medicine Oncology on Early and Late stage development projects through innovative translational research approaches

* Connect and collaborate with global heads of Research and Clinical Oncology to ensure programs are biologically sound, move the pipeline forward and are in alignment with diagnostic and biomarker strategies

* Influence corporate decisions with regard to the design and selection of New Molecular Entity (NME), ESR/LSR, IND, Early Development Go/No Go and regulatory approvals

* Establish and maintain strong external partnerships with key opinion leaders, academic institutions and other external partners and seen as a scientific thought leader in the field of oncology translational research

* Assess and identify the need for adjustments and if needed drive change within Translational Medicine Oncology organization to enhance value creation and generation

* Accountable for the Translational Medicine Oncology organization on key governance committees in Research (RRC) and Early Development (DRC) on decisions that affect biomarker deliverables

* Act as a thought leader and active member of the Translational Medicine leadership team aware of innovative approaches and external competition so that they can influences strategies and guides direction of key initiatives

* Accountable and provides transparency for allocation of Biomarker sub Team resources for projects and activities to drive prioritization that best benefits our projects and portfolio while balancing capacity resourcing requests

* Develop internal talent by creating and providing opportunities for scientific, functional and technical leadership, project responsibilities, matrix leadership and people management that meet the needs for now and in the future

* Creates an inclusive and inspiring scientific environment through senior leaders in order to deliver a diverse and highly productive organization that can attract and retain the best talent

* Responsible for prioritize resources to ensure optimal delivery of initiatives within budget and defined timelines

Key Qualifications, Attributes and Experience:

* Ph.D., M.D., or M.D. /Ph.D. in Biology, Molecular Biology or related fields with strong experience and expertise in scientific drug development

* 15+ years of progressive experience in a science based organization leading significant Oncology biomarker and diagnostic efforts. Strong background in cancer biology, cancer genetics and immunology required

* In-depth understanding and recognized scientific leader in drug and biomarker development processes and regulatory requirements from discovery through post marketing

* Proven leadership capabilities in building, developing, motivating and retaining effective teams that foster productive collaborations so that they deliver exceptional results

* Exceptional communication, influencing and partnering skills in a matrixed environment

* Demonstrated innovation ability as evidenced by patents, publications and products

Relocation benefits are available for this job posting.

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